Structure of PDB 8iya Chain C

Receptor sequence
>8iyaC (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
SKLLSTSAKRIQKELADITLDPPPNSSAGPKGDNIYEWRSTILGPPGSVY
EGGVFFLDITFTPEYPFKPPKVTFRTRIYHPNINSQGVICLDILKDNWSP
ALTISKVLLSISSLLTDPNPADPLVGSIATQYMTNRAEHDRMARQWTKRY
AT
3D structure
PDB8iya Complex of SETDB1-derived peptide bound to UBE2E1
ChainC
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.23: E2 ubiquitin-conjugating enzyme.
2.3.2.24: (E3-independent) E2 ubiquitin-conjugating enzyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C G88 E92 G47 E51
BS02 peptide C N125 S126 C131 L165 V166 G167 S168 N84 S85 C90 L124 V125 G126 S127
External links
PDB RCSB:8iya, PDBe:8iya, PDBj:8iya
PDBsum8iya
PubMed38341401
UniProtP51965|UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E1 (Gene Name=UBE2E1)

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