Structure of PDB 8itn Chain C

Receptor sequence
>8itnC (length=345) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
YAIPVDENGHRYVGLVNQAMTCYLNSLVQSLYMTPEFRNAMYDKAEQSIP
CQLQKLFLLLQTSENDSLETKDLTQSFGWTSNEAYDQHDVQELCRLMFDA
LEHKWKGTEHEKLIQDLYRGTMEDFVACLKCGRESVKTDYFLDLPLAVKP
FGAIHAYKSVEEALTAFVQPELLDGSNQYMCENCKSKQDAHKGLRITQFP
YLLTIQLKRFDFDYNTMHRIKLNDKMTFPDVLDLNDYVCVGQPIDHAAVD
DIVKTSGDNVYELFSVMVHSGNAAGGHYFAYIKNLDQDRWYVFNDTRVDF
ATPLEIEKSFGGHPSSNTNAYMLMYRRIDPKRNARFILSNQLPQH
3D structure
PDB8itn Structural and functional characterization of USP47 reveals a hot spot for inhibitor design
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C C218 C221 C271 C274 C128 C131 C181 C184
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:8itn, PDBe:8itn, PDBj:8itn
PDBsum8itn
PubMed37740002
UniProtQ22240

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