Structure of PDB 8ike Chain C

Receptor sequence
>8ikeC (length=60) Species: 9606 (Homo sapiens) [Search protein sequence]
RPATILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQ
RAKMKKLARR
3D structure
PDB8ike Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K219 R222 Q244 R247 K251 K23 R26 Q48 R51 K55
BS02 dna C T200 V241 W242 N245 T4 V45 W46 N49
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8ike, PDBe:8ike, PDBj:8ike
PDBsum8ike
PubMed
UniProtQ8TE12|LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (Gene Name=LMX1A)

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