Structure of PDB 8ik5 Chain C

Receptor sequence
>8ik5C (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
HMHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV
QVWFQNQRAKMKKLARR
3D structure
PDB8ik5 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
ChainC
Resolution1.989 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C K196 R199 K219 R222 Q244 R247 K7 R10 K30 R33 Q55 R58
BS02 dna C R199 T200 V241 N245 K249 R10 T11 V52 N56 K60
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8ik5, PDBe:8ik5, PDBj:8ik5
PDBsum8ik5
PubMed
UniProtQ8TE12|LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (Gene Name=LMX1A)

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