Structure of PDB 8ijq Chain C

Receptor sequence
>8ijqC (length=264) Species: 9606 (Homo sapiens) [Search protein sequence]
RLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDS
VPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLR
CFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTC
GDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHE
HYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVN
GTVPNEYCWPFSKP
3D structure
PDB8ijq Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis.
ChainC
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.8.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 16C C F163 M170 G208 M209 C212 R243 F283 D295 G300 H301 V304 F20 M27 G65 M66 C69 R100 F140 D152 G157 H158 V161
Gene Ontology
Molecular Function
GO:0016780 phosphotransferase activity, for other substituted phosphate groups

View graph for
Molecular Function
External links
PDB RCSB:8ijq, PDBe:8ijq, PDBj:8ijq
PDBsum8ijq
PubMed38388831
UniProtQ96LT4|SAMD8_HUMAN Sphingomyelin synthase-related protein 1 (Gene Name=SAMD8)

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