Structure of PDB 8i6j Chain C

Receptor sequence
>8i6jC (length=500) Species: 9606 (Homo sapiens) [Search protein sequence]
RKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILRE
IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHP
TVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWS
SLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVM
INKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQ
MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTD
NNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDP
KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVA
HALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAK
HTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRI
3D structure
PDB8i6j The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state
ChainC
Resolution3.82 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C G94 T95 T96 S97 E497 G75 T76 T77 S78 E478
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0044183 protein folding chaperone
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0050821 protein stabilization
GO:0051086 chaperone mediated protein folding independent of cofactor
GO:0061077 chaperone-mediated protein folding
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body
Cellular Component
GO:0002199 zona pellucida receptor complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0044297 cell body
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i6j, PDBe:8i6j, PDBj:8i6j
PDBsum8i6j
PubMed38307855
UniProtP49368|TCPG_HUMAN T-complex protein 1 subunit gamma (Gene Name=CCT3)

[Back to BioLiP]