Structure of PDB 8i3y Chain C

Receptor sequence
>8i3yC (length=464) Species: 185431 (Trypanosoma brucei brucei TREU927) [Search protein sequence]
GLDKVMSLSSAVQDIKNGATLAVGGFGTGGMPHAIMQEIKKMGVRDLIIY
SDGAGVDGYGIGVLFENKQINKMIVSYVGNNKIFARQYLEGDVELEFCPQ
GSLAERMRAGGAGIPAFYTPTAVGTVLQTGGQITKYDKNGGVLKESTPRE
TRFFGGRLYCLENAIKTDFSIVKAWKGDRCGNLVFRGTARNFNVPVGQCG
QTVIAEVENLVENGDIDPDEVHLPGVYVDRVVVPERYQTLIEHRTVTRVR
QRIARRAALEFANGMYVNLGIGIPTESSNYIPAGVNVVLQSENGLIGMGP
FPTEDKVDADWINAGKQTISHLAGSALFDSATSFAMIRGGHMDLTMLGAL
EVAANGDLANFMIPGKLVKGPGGAMDLVSCGTRVVVTTTHCNKNGDPKIV
ERCRLPVTGKHCVCRIITEYAVFDVVDGRLVLKEIAEDTTVDQVKKLTGV
GFDADNVITMPLAP
3D structure
PDB8i3y Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.3.5: 3-oxoacid CoA-transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C Q211 D239 Q201 D229
Gene Ontology
Molecular Function
GO:0008260 succinyl-CoA:3-oxo-acid CoA-transferase activity
GO:0008410 CoA-transferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0046950 cellular ketone body metabolic process
GO:0046952 ketone body catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i3y, PDBe:8i3y, PDBj:8i3y
PDBsum8i3y
PubMed
UniProtQ386P1

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