Structure of PDB 8hsr Chain C

Receptor sequence
>8hsrC (length=367) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RLVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQ
ARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETT
PDELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIK
VIVLLIDERPEEVTDFRESVQGAEVIASTFDEPPQNHIRVAEFVHERAKR
IVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLG
AARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEER
RIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLAR
LARTKNNKEFLASLAAR
3D structure
PDB8hsr Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
ChainC
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C T291 G295 R333 T232 G236 R274
BS02 ADP C K187 G189 K190 T191 T192 L193 F362 K128 G130 K131 T132 T133 L134 F303
BS03 MG C T191 E217 T132 E158
BS04 BEF C E217 R218 R276 E158 R159 R217
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006353 DNA-templated transcription termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8hsr, PDBe:8hsr, PDBj:8hsr
PDBsum8hsr
PubMed36753546
UniProtQ5SJE9

[Back to BioLiP]