Structure of PDB 8h65 Chain C

Receptor sequence
>8h65C (length=166) Species: 9606 (Homo sapiens) [Search protein sequence]
GIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDP
KHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMN
HLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYE
GATLMECELNPRIPYT
3D structure
PDB8h65 Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BCO C Q530 L531 M534 V577 C579 A580 V581 Q586 V587 G589 G591 T592 Y613 Y617 A618 G620 Y621 K624 Q34 L35 M38 V81 C83 A84 V85 Q90 V91 G93 G95 T96 Y117 Y121 A122 G124 Y125 K128
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function
External links
PDB RCSB:8h65, PDBe:8h65, PDBj:8h65
PDBsum8h65
PubMed37040526
UniProtQ92830|KAT2A_HUMAN Histone acetyltransferase KAT2A (Gene Name=KAT2A)

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