Structure of PDB 8h3h Chain C

Receptor sequence
>8h3hC (length=528) Species: 9606 (Homo sapiens) [Search protein sequence]
SSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPG
TGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQA
YQMRPSIIFFDQIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVV
IGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPL
DTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLS
SINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEAL
QRVFPHAYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIP
VLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFT
TLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPDKEE
RTKFFEDLILKQAAKPPHERLKNLLKTVVKKSQNYNIFQLENLYAVISQC
IYRHRKDHDKTSLIQKMEQEVENFSCSR
3D structure
PDB8h3h Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
ChainC
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C S427 G429 G470 G472 K473 T474 L475 H611 G636 A637 K640 S7 G9 G50 G52 K53 T54 L55 H191 G216 A217 K220
BS02 ATP C R586 R589 R166 R169
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:8h3h, PDBe:8h3h, PDBj:8h3h
PDBsum8h3h
PubMed37770645
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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