Structure of PDB 8gan Chain C

Receptor sequence

>8ganC (length=283) Species: 486 (Neisseria lactamica) [Search protein sequence]

TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNNLIDEAHEQENVKGKEKGEKTEAARQY
MCSRYYDIRTFGAVMTTGKNAGQVRGPVQLTFSRSIDPIMTLEHSITRMA
VTNEKDASETGDNRTMGRKFTVPYGLYRCHGFISTHFAKQTGFSENDLEL
FWQALVNMFDHDHSAARGQMNARGLYVFEHSNNLGDAPADSLFKRIQVVK
KDGVEVVRSFDDYLVSVDDKNLEETKLLRKLGG

3D structure

PDB

8gan Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.

Chain

Resolution

3.26 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	P20 G22 P24 V44 C45 K47 R48 R51 R68 F112 Q124 V125 R126 Q130 I147 T148 R149 M150 R165 M167 S215 R218	P19 G21 P23 V43 C44 K46 R47 R50 R67 F111 Q123 V124 R125 Q129 I146 T147 R148 M149 R164 M166 S214 R217
BS02	dna	C	V115 T117 T153 N154 D157 R165 M167 G168	V114 T116 T152 N153 D156 R164 M166 G167

Gene Ontology

	Biological Process
GO:0043571	maintenance of CRISPR repeat elements

View graph for
Biological Process

External links

PDB	RCSB:8gan, PDBe:8gan, PDBj:8gan
PDBsum	8gan
PubMed	38242128
UniProt	D0W8X6

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