Structure of PDB 8g3z Chain C

Receptor sequence
>8g3zC (length=390) Species: 11520 (Influenza B virus) [Search protein sequence]
EPEWTYPRLSCPGSTFQKALLISPHRFGEIKGNSAPLIIREPFIACGPTE
CKHFALTHYAAQPGGYYNGTREDRNKLRHLISVKLGKIPTVENSIFHMAA
WSGSACHDGKEWTYIGVDGPDSNALLKIKYGEAYTDTYHSYAKNILRTQE
SACNCIGGDCYLMITDGPASGVSECRFLKIREGRIIKEIFPTGRVKHTEE
CTCGFASNKTIECACRDNRYTAKRPFVKLNVETDTAEIRLMCTETYLDTP
RPNDGSITGPCESDGDKGSGGIKGGFVHQRMASKIGRWYSRTMSKTKRMG
MGLYVKYDGDPWTDSEALALSGVMVSMEEPGWYSFGFEIKDKKCDVPCIG
IEMVHDGGKTTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
3D structure
PDB8g3z A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C D293 T297 D324 G344 G346 D217 T221 D248 G268 G270
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g3z, PDBe:8g3z, PDBj:8g3z
PDBsum8g3z
PubMed37258672
UniProtR4KV67

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