Structure of PDB 8g1q Chain C

Receptor sequence
>8g1qC (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
VLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHS
YRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKER
CLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQE
3D structure
PDB8g1q Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
ChainC
Resolution3.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YHB C W88 Y98 R107 I109 H110 S111 Y112 H115 W117 W27 Y37 R46 I48 H49 S50 Y51 H54 W56
External links
PDB RCSB:8g1q, PDBe:8g1q, PDBj:8g1q
PDBsum8g1q
PubMed37443112
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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