Structure of PDB 8g0u Chain C

Receptor sequence
>8g0uC (length=455) Species: 5207 (Cryptococcus neoformans) [Search protein sequence]
NYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQW
FPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCR
VANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAE
SLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLR
RTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTPKGVVHS
TAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITT
AVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLHVKNHDLSSLRVL
GSVGEPIGKNQCAIVDTYWMTETGSISIAPLPTFPFFGMDVDIIDPQTGQ
VLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAA
RMWIK
3D structure
PDB8g0u Crystal Structure of Acetyl-CoA synthetase in complex with an isopropyl ester AMP inhibitor from Cryptococcus neoformans H99
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.1: acetate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YHQ C G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 G354 E355 P356 D366 T367 Y368 W369 M370 T371 D447
Gene Ontology
Molecular Function
GO:0003987 acetate-CoA ligase activity
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006085 acetyl-CoA biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g0u, PDBe:8g0u, PDBj:8g0u
PDBsum8g0u
PubMed
UniProtJ9VFT1

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