Structure of PDB 8fzk Chain C

Receptor sequence
>8fzkC (length=422) Species: 9606 (Homo sapiens) [Search protein sequence]
WSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFV
SFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH
AHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGY
LRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI
SYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTD
EQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVN
HGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL
MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEA
LQNHENESVYKASLSLIEKYFS
3D structure
PDB8fzk Dimeric human importin alpha subunit
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C T349 Q352 D390 T393 T274 Q277 D315 T318
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fzk, PDBe:8fzk, PDBj:8fzk
PDBsum8fzk
PubMed
UniProtP52292|IMA1_HUMAN Importin subunit alpha-1 (Gene Name=KPNA2)

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