Structure of PDB 8f5p Chain C

Receptor sequence
>8f5pC (length=1176) Species: 5689 (Leishmania tarentolae) [Search protein sequence]
MHTSVRWSETADAVKGIRPPVNSLCYSPSGDYVVASCGVRVLVYAASTGT
LLHSLMGHQDTIYCVDYSSDGKNFASGGADRTVIVWSSQGEGIVKYQHTE
AIQALAHNPTSSQLASVSSVDWGIWSPEQPKVSKYSLPSKGLCAAWTPNG
KTLAIGMLDGTVMMLSKTSEEKVIIRRPAPVWALAFTPLRENGIDVLAIG
SWDQRLSFYNLSGTAVGRERELDFDPCSVSYFNDGEYILLSGSDHKVTLF
TKDGNRLIELASADDWIWSARQRPRQKQFCYGTNDGTISCIDITISTVHT
IYDDQYVFRKDMTNLVVHQLLVDRKMVIPCNEYVQKIATFLDKLAVQLQE
RVIVFEFFYDDDRTMRYQDIAQIRRRLECSLLCVTTGAIIVSNDKRITMY
DFQGNKRREWSMESPVQLMKVVGGMEGREILLVGLNGGQVMKVFVDNPFP
TLLHKGTAPVKSAELSSSRSRLAVIDSTNTLQVLELGEKNELLFSEDNVT
AVAFNIDVDDNIAFTTGDNTLHIKTGSLPAYQQAVRGIVVGFKANHVFNL
HYSNMMVLDVPHAHALYKYVEMRDFDRAYEVACLGVADADWKMLGLHAMS
QLRLDIARKAFTHIQDTKLVELLKSLELRRRQKDSVLYGSILAFQGKYND
AARQFMKTGCELKAVEMYCDLKMWDNAKKICTDEKVLKDLIRQQARWAEE
SQNFVEAASLYESCGDYAKAIGMMGQAGQVEKLMKMCRSLPTSEVTLITE
CANFFRKHNAIPFAIEAYEKVQDHQALIGIYVAKGDWRNAFTILEKTPTL
AREVYVPWATWLADNDKFDEALEAFRAAKWPKEAMRLMETLATNSVTCRK
FRDAAFYYIHLAEEYGRFEETEKPTDVEKAARIRRSKECVRRADIYYAFS
GVYAHTTQPLPYNELSLFRTAKYLFGMCAESAIPINVGKGAILYTLSRIA
NRLEMVRTARAVFEKLQGVILPVSMMEQVDIETLLVRSKPVKDRDELLDR
CFRCNQLIAQLPMAGDRCPNCFHPCVRSFVNFECLPLVEFVLADELTDEE
AERIIVSGNDPFFTQLQYVLRPGRPTATYQPFVASADILKGFRRDEVFIV
RPRYGTLPVPNRYYRLMRSDVSVCLCNGCQHFFIAEDYEAECMRGSGCPL
CRYRPGKQVSRSMKQILFDMETAAAA
3D structure
PDB8f5p Mechanism of IFT-A polymerization into trains for ciliary transport.
ChainC
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C C1044 C1047 C1061 C1064 C1001 C1004 C1018 C1021
BS02 ZN C C1232 C1235 C1254 C1257 C1126 C1129 C1148 C1151
Gene Ontology
Biological Process
GO:0035721 intraciliary retrograde transport
GO:0060271 cilium assembly
GO:0061512 protein localization to cilium
GO:1905515 non-motile cilium assembly
Cellular Component
GO:0030991 intraciliary transport particle A
GO:0097730 non-motile cilium

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8f5p, PDBe:8f5p, PDBj:8f5p
PDBsum8f5p
PubMed36563665
UniProtA0A640KU89

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