Structure of PDB 8evc Chain C

Receptor sequence
>8evcC (length=441) Species: 9606 (Homo sapiens) [Search protein sequence]
IVVDPSSNLYYRWLTAIALPVFYNWYLLICRACFDELQSEYLMLWLVLDY
SADVLYVLDVLVRARTGFLEQGLMVSDTNRLWQHYKTTTQFKLDVLSLVP
TTNYPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHW
NACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIYSLYWSTLTLTTI
GETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAK
IDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKA
EIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIG
KEMYIINEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTA
NIRSIGYSDLFCLSKDDLMEALTEYPEAKKALEEKGRQILM
3D structure
PDB8evc Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
ChainC
Resolution3.33 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG C G548 I550 R564 T565 K601 G382 I384 R398 T399 K435
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8evc, PDBe:8evc, PDBj:8evc
PDBsum8evc
PubMed37463923
UniProtQ16281|CNGA3_HUMAN Cyclic nucleotide-gated channel alpha-3 (Gene Name=CNGA3)

[Back to BioLiP]