Structure of PDB 8eph Chain C

Receptor sequence
>8ephC (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
DGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCE
QFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSV
3D structure
PDB8eph An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa.
ChainC
Resolution1.88 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC C S61 W72 S15 W26
BS02 CA C D47 G48 Q50 D64 D65 D1 G2 Q4 D18 D19
External links
PDB RCSB:8eph, PDBe:8eph, PDBj:8eph
PDBsum8eph
PubMed38985762
UniProtP00740|FA9_HUMAN Coagulation factor IX (Gene Name=F9)

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