Structure of PDB 8ep7 Chain C

Receptor sequence
>8ep7C (length=328) Species: 261594 (Bacillus anthracis str. 'Ames Ancestor') [Search protein sequence]
MKTYYEQDANVGLLQGKTVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGK
SFEVAKADGFEVMSVSEAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQ
MLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGNGVPALVA
VHQDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGG
VTALVKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSIS
DTAEFGDYVTGSRIVTDETKKEMKRVLTEIQQGEFAKKWILENQAGRPTY
NAMKKAEQNHQLEKVGEELREMMSWIHA
3D structure
PDB8ep7 Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in the complex with NADP.
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C Y24 G25 S26 Q27 R47 S51 L78 L79 P80 D81 Q83 V87 H106 Y24 G25 S26 Q27 R47 S51 L78 L79 P80 D81 Q83 V87 H106
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ep7, PDBe:8ep7, PDBj:8ep7
PDBsum8ep7
PubMed
UniProtQ81S27|ILVC2_BACAN Ketol-acid reductoisomerase (NADP(+)) 2 (Gene Name=ilvC2)

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