Structure of PDB 8ei1 Chain C

Receptor sequence
>8ei1C (length=337) Species: 9606 (Homo sapiens) [Search protein sequence]
DETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQI
CEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRT
YVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAI
DRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEY
LHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNN
LLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDK
TMRQELDDFKDKVDHIIDICFLKNEKFINAMKEAFET
3D structure
PDB8ei1 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
ChainC
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C V488 M497 R498 K527 F530 E531 V293 M302 R303 K332 F335 E336
Gene Ontology
Molecular Function
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8ei1, PDBe:8ei1, PDBj:8ei1
PDBsum8ei1
PubMed37914719
UniProtQ13620|CUL4B_HUMAN Cullin-4B (Gene Name=CUL4B)

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