Structure of PDB 8eho Chain C

Receptor sequence
>8ehoC (length=166) Species: 28344 (Porcine reproductive and respiratory syndrome virus) [Search protein sequence]
PVPTCGITTYSPPTDGSCGWHVLAAIMNRMINGDFTSPLTQYNRPEDDWA
SDYDLVQAIQCLQLPATVVRNRACPNAKYLIKLNGVHWEVEVRSGMAPRS
LPRECVVGVCSEGCVAPPYPADGLPKRALEALASAYRLPSDCVSSGIADF
LANPPPQEFWTLDKML
3D structure
PDB8eho Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis
ChainC
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C C485 C516 C521 C525 C74 C105 C110 C114
BS02 3CN C G427 C429 W460 V497 G16 C18 W49 V86
Gene Ontology
Biological Process
GO:0016032 viral process
GO:0019082 viral protein processing

View graph for
Biological Process
External links
PDB RCSB:8eho, PDBe:8eho, PDBj:8eho
PDBsum8eho
PubMed38096325
UniProtW0NX70

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