Structure of PDB 8edg Chain C

Receptor sequence
>8edgC (length=550) Species: 7370 (Musca domestica) [Search protein sequence]
MDNLEVKAKINQGLYKITPRHKGTSFIWNVLADIQKEDDTLVEGWVFCRK
CEKVLKYTTRQTSNLCRHKCCASLKQSRELKTVSADCKKEAIEKCAQWVV
RDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTS
DAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNE
LRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANV
VKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANL
QHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHIN
KSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDV
ADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEF
CLSKMEDPVCPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLAL
SLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK
3D structure
PDB8edg Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
ChainC
Resolution4.64 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R107 R586 R588 T593 R104 R527 R529 T534
BS02 dna C R149 E584 N587 R588 R146 E525 N528 R529
BS03 dna C R63 Q64 N67 K72 K92 R318 R60 Q61 N64 K69 K89 R315
BS04 dna C G26 T27 S28 R63 Q64 S66 P108 F109 S110 W319 R573 G23 T24 S25 R60 Q61 S63 P105 F106 S107 W316 R514
BS05 ZN C H71 C73 H68 C70
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8edg, PDBe:8edg, PDBj:8edg
PDBsum8edg
PubMed37491363
UniProtQ25438

[Back to BioLiP]