Structure of PDB 8e0v Chain C

Receptor sequence
>8e0vC (length=344) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIHKILKGNDDRLLV
VIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTVGWKG
LINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADL
MSWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAP
HCFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKA
GLPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLV
EGNQSLESGEPLAYGKSITDACIGWEDTDALLRQLANAVKARRG
3D structure
PDB8e0v Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN C C61 H268 E302 D326 C55 H262 E296 D320
BS02 PEP C R92 Y94 G163 A164 R165 K186 R234 H268 R86 Y88 G157 A158 R159 K180 R228 H262
BS03 GAL C Q170 E174 F209 Q164 E168 F203
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e0v, PDBe:8e0v, PDBj:8e0v
PDBsum8e0v
PubMed36197914
UniProtP0AB91|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)

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