Structure of PDB 8e0p Chain C

Receptor sequence
>8e0pC (length=782) Species: 562,10090 [Search protein sequence]
EEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAA
TGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGK
LIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQ
EPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNK
HMNADTDYSIAEHAFNHGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKG
QPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAV
ALKSYEEELVKDPRVAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAAS
GRQTVDAALAAAQTNAAAFKESQCHHMLKHLHNGARITVQMPPTIEGHWV
STGCEVRSGPEFMTRSYRFYNNNTFKAYQFYYGSNRCTNPTYTLIIRGKI
RLRQASWIIRGGTEADYQLHGVQVICHTEAVAEQLSRLVNRTCPGFLAPG
GPWVQDVAYDLWQEESNHECTKAVNFAMHELQLIRVEKQYPHHSLDHLVE
ELFLGDIHTDATQRVFYRPSSYQPPLQNAKNHNHACIACRIIFRSDEHHP
PILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYH
YSDPVCKHPTFTIYARGRYSRGVLSSKVMGGTEFVFKVNHMKVTPMDAAT
ASLLNVFSGSWQVGIQQDVTVALGIKLPHTEYEIFKMEQDTRGRYLLFNG
QRPSDGSSPDRPEKRATSYQMPLVQCASSSPR
3D structure
PDB8e0p Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein.
ChainC
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC C D17 K18 E114 E156 Y158 D12 K13 E109 E151 Y153
BS02 GLC C W65 D68 R69 E156 P157 Y158 W343 W60 D63 R64 E151 P152 Y153 W338
BS03 DMX C Y93 P94 F95 Q328 I332 Y88 P89 F90 Q323 I327
BS04 DMX C G438 T446 Y447 V486 Q489 L490 V529 G433 T441 Y442 V481 Q484 L485 V524
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:0017147 Wnt-protein binding
GO:0042802 identical protein binding
GO:1901982 maltose binding
Biological Process
GO:0001942 hair follicle development
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0034219 carbohydrate transmembrane transport
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0042956 maltodextrin transmembrane transport
GO:0043615 astrocyte cell migration
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e0p, PDBe:8e0p, PDBj:8e0p
PDBsum8e0p
PubMed37155902
UniProtC3SHQ8;
Q3U128

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