Structure of PDB 8do8 Chain C

Receptor sequence
>8do8C (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
CRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGT
QDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEF
YQKKKSRWPFSDECIPWEVWTVKVHVVERQICREKVGEKLCEKIINIVEV
MNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITD
3D structure
PDB8do8 Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation.
ChainC
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C G43 T44 Y45 I47 G41 T42 Y43 I45
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
Biological Process
GO:0000045 autophagosome assembly
GO:0006914 autophagy
GO:0008285 negative regulation of cell population proliferation
GO:0010508 positive regulation of autophagy
GO:1903059 regulation of protein lipidation
Cellular Component
GO:0000407 phagophore assembly site
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:1990316 Atg1/ULK1 kinase complex

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Cellular Component
External links
PDB RCSB:8do8, PDBe:8do8, PDBj:8do8
PDBsum8do8
PubMed36791199
UniProtQ9BSB4|ATGA1_HUMAN Autophagy-related protein 101 (Gene Name=ATG101)

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