Structure of PDB 8dey Chain C

Receptor sequence
>8deyC (length=57) Species: 9606 (Homo sapiens) [Search protein sequence]
SERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTG
HLRTHSV
3D structure
PDB8dey Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
ChainC
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LWK C H141 C142 N143 Q144 H6 C7 N8 Q9
BS02 ZN C C142 C145 H158 H162 C7 C10 H23 H27
BS03 ZN C C170 H186 H190 C35 H51 H55
External links
PDB RCSB:8dey, PDBe:8dey, PDBj:8dey
PDBsum8dey
PubMed36863346
UniProtQ9UKS7|IKZF2_HUMAN Zinc finger protein Helios (Gene Name=IKZF2)

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