Structure of PDB 8d4i Chain C

Receptor sequence
>8d4iC (length=462) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYV
FSEPEIIRNIHEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEA
NSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYEL
EHIDAISRKLKKVANVCVRVEPNVPSLVTAFHAKSGLDLEQAEETCRRIL
AMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDESRRLEEVLGIKFDLIN
VGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRTDVEIC
IEPGRKVTGSAAVLLTEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLS
DSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGEEFLLP
KETHVGDIVAFLDAGAYTIESQTVFNNRPRTGVVMIDKNGDTRLIRREDS
YEDMVKYDIYLA
3D structure
PDB8d4i The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
ChainC
Resolution1.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.116: D-ornithine/D-lysine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PUT C Q358 D361 Q353 D356
BS02 EPE C H218 G220 D221 D356 Y422 H213 G215 D216 D351 Y417
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008836 diaminopimelate decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0009089 lysine biosynthetic process via diaminopimelate

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8d4i, PDBe:8d4i, PDBj:8d4i
PDBsum8d4i
PubMed36265649
UniProtQ8ZNC4|DOKDC_SALTY D-ornithine/D-lysine decarboxylase (Gene Name=dokD)

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