Structure of PDB 8d3m Chain C

Receptor sequence
>8d3mC (length=343) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
MKKLLNTLYVTQPDTYLSLDGDNVVLLKEQEKLGRLPLHNLEAIVGFGYT
GASPALMGYCAERNISITFLTKNGRFLARVVGESRGNVVLRKTQYRISEN
DQESTKIARNFITGKVYNSKWMLERMTREHPLRVNVEQFKATSQLLSVMM
QEIRNCDSLESLRGWEGQAAINYNKVFDQMILQQKEEFAFHGRSRRPPKD
NVNAMLSFAYTLLANDVAAALETVGLDAYVGFMHQDRPGRASLALDLMEE
LRGLYADRFVLSLINRKEMTADGFYKKENGAVLMTDEARKTFLKAWQTKK
QEKITHPYLGEKMSWGLVPYVQALLLARFLRGDLDEYPPFLWK
3D structure
PDB8d3m PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
ChainC
Resolution3.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C Y49 N73 N215 R289 K290 L293 Q297 Y49 N73 N215 R289 K290 L293 Q297
BS02 dna C D14 Y49 D14 Y49
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8d3m, PDBe:8d3m, PDBj:8d3m
PDBsum8d3m
PubMed36272411
UniProtQ9KFX9

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