Structure of PDB 8cy5 Chain C

Receptor sequence
>8cy5C (length=539) Species: 1496 (Clostridioides difficile) [Search protein sequence]
IYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDILYD
LFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDSLT
NKIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEKKYKKFLLEKYSE
VYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESLSGKDLREYIKSN
VNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYIDVFKIKNEDICIN
KFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKCKYSL
EDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVD
KSEYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQ
WGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKF
SYEYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVMKIRIFRDNNYEE
IENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLGI
3D structure
PDB8cy5 Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8cy5, PDBe:8cy5, PDBj:8cy5
PDBsum8cy5
PubMed36581322
UniProtQ183J3

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