Structure of PDB 8cxv Chain C

Receptor sequence
>8cxvC (length=540) Species: 272563 (Clostridioides difficile 630) [Search protein sequence]
GIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDILY
DLFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDSL
TNKIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEKKYKKFLLEKYS
EVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESLSGKDLREYIKS
NVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYIDVFKIKNEDICI
NKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKCKYS
LEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIV
DKSEYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYEL
QWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDK
FSYEYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVMKIRIFRDNNYE
EIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLGI
3D structure
PDB8cxv Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
ChainC
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8cxv, PDBe:8cxv, PDBj:8cxv
PDBsum8cxv
PubMed36581322
UniProtQ183J3

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