Structure of PDB 8ctm Chain C

Receptor sequence
>8ctmC (length=305) Species: 5661 (Leishmania donovani) [Search protein sequence]
PRKIILDCDPGIDDAVAIFLAHGNPEVELLAITTVVGNQTLEKVTRNARL
VADVAGIVGVPVAAGCTKPLVRGVGETGMGNVSYPPEFKTKLDGRHAVQL
IIDLIMSHEPKTITLVPTGGLTNIAMAVRLEPRIVDRVKEVVLMGGGYHT
GNASPVAEFNVFVDPEAAHIVFNESWNVTMVGLDLTHQALATPAVQKRVK
EVGTKPAAFMLQILDFYTKVYEKERNTYATVHDPCAVAYVIDPTVMTTEQ
VPVDIELNGALTTGMTVADFRYPRPKHCHTQVAVKLDFDKFWCLVIDALK
RIGDP
3D structure
PDB8ctm Crystal structure of the nucleoside hydrolase from Leishmania donovani.
ChainC
Resolution1.73 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.2.1: purine nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C D10 D15 T126 D241 D9 D14 T118 D233
BS02 CA C H23 L30 H22 L29
Gene Ontology
Molecular Function
GO:0008477 purine nucleosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0045437 uridine nucleosidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006152 purine nucleoside catabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ctm, PDBe:8ctm, PDBj:8ctm
PDBsum8ctm
PubMed
UniProtQ8WQX2

[Back to BioLiP]