Structure of PDB 8cdu Chain C

Receptor sequence
>8cduC (length=708) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
KEAFMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEK
GLIVRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDTSLSDVFIPPNE
LNTAMNGDIVMVRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGF
VIPDDKKITSDIFIPKNGKNGAAEGHKVVVKLTSYPEGRMNAEGEVETIL
GHKNDPGIDILSVIHKHGLPGEFPADAMEQASSTPDTIDEKDLKDRRDLR
DQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHYVTENSPIDK
EALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQ
VTEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERL
AQILRDKRMDRGAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFM
LVANETVAEHFHWMNVPFIYRIHEEPNAEKLQKFLEFVTTFGYVVKGTAG
NIHPRALQSILDAVRDRPEETVISTVMLRSMKQAKYDPQSLGHFGLSTEF
YTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERLPDIAEHTSS
MERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIE
GLVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERN
IDFEIVGM
3D structure
PDB8cdu Structural basis of ribosomal 30S subunit degradation by RNase R
ChainC
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.1: exoribonuclease II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C T147 R148 N149 E176 R191 K205 T145 R146 N147 E174 R189 K203
BS02 rna C A264 F418 F420 E422 R439 R441 R473 L530 K534 Q535 A536 H545 L548 Y553 R561 R562 E611 R612 F644 A262 F416 F418 E420 R437 R439 R471 L528 K532 Q533 A534 H543 L546 Y551 R559 R560 E609 R610 F642
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0016070 RNA metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cdu, PDBe:8cdu, PDBj:8cdu
PDBsum8cdu
PubMed38326618
UniProtO32231|RNR_BACSU Ribonuclease R (Gene Name=rnr)

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