Structure of PDB 8cap Chain C

Receptor sequence
>8capC (length=244) Species: 142864 (Cylindrospermum stagnale) [Search protein sequence]
EPTFVVNASLLPSKVLGLQVQRPQSFNYQPGDYLFIKCPGISKFEWHPFT
ISSAPEMPDVLTLHIRAVGSWTGKLYQLIREQREEWIRSGSSPGVPVYID
GPYGTPSTHIFESKYAILICAGIGVTPFASILKSILHRNQQNPAKMPLKK
VHFYWLNREQKAFEWFVELLSKIEAEDTNNLFDLNLYLTSRTKTGRPDWE
EIFKDVAKQHAPDNVEVFFCGPTGLALQLRHLCTKYGFGYRKEN
3D structure
PDB8cap Targeting ROS through the discovery of isoform-selective NADPH oxidase inhibitors
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD C L675 R678 L227 R230
BS02 FAD C Y445 H459 P460 F461 T462 H476 I477 R478 V480 G481 S482 W483 T484 T541 Y33 H47 P48 F49 T50 H64 I65 R66 V68 G69 S70 W71 T72 T126
BS03 U4O C V427 H476 I538 F578 V15 H64 I123 F163
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:8cap, PDBe:8cap, PDBj:8cap
PDBsum8cap
PubMed37884805
UniProtK9WT99

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