Structure of PDB 8bzl Chain C

Receptor sequence
>8bzlC (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKAKL
QDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVT
VEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTY
HAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQGGK
NIELAVMRRDQSLKILNPEEIEKYV
3D structure
PDB8bzl Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration.
ChainC
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C A25 K28 S30 K61 A74 G75 L76 T77 A24 K27 S29 K58 A71 G72 L73 T74
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bzl, PDBe:8bzl, PDBj:8bzl
PDBsum8bzl
PubMed
UniProtO14818|PSA7_HUMAN Proteasome subunit alpha type-7 (Gene Name=PSMA7)

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