Structure of PDB 8bwy Chain C

Receptor sequence
>8bwyC (length=4264) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence]
SKRIAWMKTTICDSLQLKDMIVEESFQYEKNKNLLEQFLSGEGLNKIFAY
YQVQEQAQNDDIKDTGAQDPVLFFTTGDLEKIQDKAVWFLRITNPADDKK
KASQQDGNDNDIIFGEITPNTVPMLNALMESVYSRQIDHIITEKIQFWGV
AEEEQVLEFQQHSNKFSSEVREANLMSPGTEHFKLDYEAISGLSESEKMQ
HYEMKFNEWINLISSQLNRKDEKDAGPATELIYWRSRMQKITNWSEQLKS
KDFQIVKASLQRHKNHDNQRPRGDESLNEAKDNVKYLTTLEKFIEPLYNG
TPQQIIDTLPALMNAIKMIHTIARFYNTTDKMTGLFIKITNQMIKNCKDR
ILNMIWEQDPAELIEVLGSCIKLYCEYKKCYNDTKEKVADMPKGKTFDFS
DAQIFGKFDTFVRRLQKLIEIFSNIQQFNALAKHNLEGMDVLTNKFKKII
DDFKKKGHNLLDTANNKFDRDWVEFNVEISHLDGELQNFIDNNFNRFRNI
EYSLKLLHKFQSTIKRDSLKHNLTSRYNAILHNYATELDTIQRVFQDQKS
NPPLVRNMPPEAGKIIWARHLFQKITGPINIFPENVINSTEIRRYYGSYN
TLGKQLTIYEMWFYQDWVNKIEQSKAALQATLIVRHDENKKLYVNFDLEI
MQLIREAKCLDRQGIEIPESARIILLQEDKFKTYYNELLYALKEYERINS
KIKPICKNLLLPHIEDLDLKLRPGMVTLTWTSMNIESYLYYVHQGLKKLE
QLIINVNDIIENRIENNLKTVSKVVLVHLPNVEVERAVDDLLQTIMLYPL
DPHVDPVLPEETKRIKRYYFWYFYQALLNSTQNSLNAMKYRVCGKKIPGA
NTLQNLKPFFQVEVQLNGDKVTLNPSLQEIQKSINRAATAVLRCSKHLYN
WDQQNKDSTDKATFYDMIACDKEIVKVILLLTGSIQGTKNKVNEFLSGFT
KFEWLCKESIQESIKKFSKNGPTLQNYEDQLKKFSQIEEEIEKIVPTYKI
GAMELMTHNICTSLSTWAKEWKLQYSQDLHKRARQLLDSLTEQTKMLSTK
LSKPVKDIDSLGYVMETLEQIRKEQAEIDMKFNPVQEMYSLLDNYLPGGI
TDKDEMDARSLLRRNWDILIQQAEIKGKEYQHKQAIYLKELKQSIKDFTN
QVSIFRRDYEKNGPMVEGISPAEAMERLRRFEDEYDVKYQMYKINARGEN
LFGMQFQFGIWGKRDVPCMLNGLIVGTILERLEEDQLQLSTFNSQRHVTP
FKAEVENLIRTFSDVNDTLDMWVKVQKLWTSLEPVFTGGDIARQMPLQAK
QFQGIDKNWMKIMEKAVETKKVIPCCQNDMLKDFLPDLNRKLEDCQKMLE
AYLEGKRKKFPRFYFVSNPTLLKILSQGSEPTSIQEDFEKLFDAITKVTF
ESAKDKKNPALKQITQIQQVIGRNEENISLTGYYVKCEGNIEDWLKKLEQ
NMQQTLKDIASAAAQQVFQVGLKEFVSSQASQIALLGLQILWTSKVNEGL
ERLSRNERNAMDIKRNEIKEHMNILSSMCLEDLNGAVERTKVETLVTIQV
HQKDISMDLKCKDVNDFEWQKQTRIAWKTDIDECIISITDWDSPYSYEFL
GAKERLCITPLTDRCYITLAQAMSMYYGGAPAGPAGTGKTETVKDLGRTL
GVFVVVTNCSDQHRYRDMAKIFKGLVQSGLWGCFDEFNRIDLEVLSVVAM
QVESITTARKQHMKKFMFPEEEIEIELIPTVSYFITMNPGYAGRQELPEN
LKVLFRGVSMMVPDREIIIKVKLASVGYLQIDLLAKKFNVLYRLCEEQLS
KQRHYDFGLRNILSVLRTAGNTKRQEIKSDEEMLLMRSLRDMNLSKLVAD
DIPLFNGLLADIFPKLKEVPKKLYPDVEKKIPEEINAESYLINTPSFQLK
IIQLYETCLVRHGFMLVGPTGSGKSTIMKILTEVLTKLGSPHKIVIMNPK
AITAEQMYGVKSEISDDWIPGVFSTIWAKSNNRALKHTTWITCDGPVDAI
WIENLNTVLDDNKILTLANGERIAMTENCKVVFEVENLNNASPATVSRCG
QVYVSPTDLGYEAVIEGWIRNRKASGRAEESDKLGNILRKYLINMRFIEL
QSKECKEPMMDTSPVISVINILNLLTGCLQYFVQTQRTLSEQEYEKFIVY
SMAWAIGGIYEAQDRVRFHELLLAKNAPIPQKGKENETVFDYYVSQDYLD
WKICSPEEWVPPQSLQFSQLLLPTLDSFRAEMLLNFILTQPKSHTCSNSA
LLIGGSGTAKTSSVLLYCNKFDPQKMLFKRTNFSSATSPFMFQSTIEAEC
DFKVGKEFAPPGNKMMTIFIDDMSMPFVNKWGDQITLELVRQLIETGGFY
MLDKTQRGNQRKMKNLQYIGAMNHPGGGRNDIPNRLKRQFFIFNMILPLS
IEGIYGPIIKHMFKQKYFSDSTYKVIESLTSATIALWNKVKSTMLPTPAK
FHYVFNMRELSRIFKGILTCKKDTINDAPKSMKIKPELFLVGLWRHEAER
VLADKLVNNKDKDTVMGYIQEVSLESFSQIENEILEKYSSEKTFLFCDFL
RPDVINEDGIIEEEAPKIYEAIDSLTELRKRCNFLLSFYNDRNPSKKMPL
VLFDDALKHLLRISRIIRQPRSSGLLVGVGGSGKQSLTRLAGFIGKNLIQ
QIIVTKTYSDKDLKEDIKKGFDDAGHLGKQVTFLMTDSEVKKEEFLEYIN
MVLSTGEIPNLLAKDEREVWLGDISQAYCKEKNLGNIDPPQSELWTYFVD
RVRDNFHIMLCFSPVGQKFRERARKFPALFNECTIDWFLPWPEEALVSVA
ETFIKNFDKLDTKEETKQELMKHMGNVHLMVNEICDEYYQKMRRQVYVTP
KSFLSYLNSYKTLYIEKYDELDQQEESFKIGLNKIQEATITINQMEISLK
EEEIQLNEATEKTNQLLANLDKESKKANQKGEEVAATNKQCEIQAEQISK
EKEEAERELEAALPALRRAQEAVDSIESKDIVELKANKKPLDIIKYIMDA
VLVFFKARLSYDESGIQTLGDMNFMKKLKEFEKDSINEETIELLEPYLNQ
SEFNDTFATKASKAAAGILKWAFAIYEYHQKSKIVKPKRIQVAIAEGRQA
IALKELEKAREDLAQIQAYIKNLKDVYTKQMEEKNELEMKAAKTKKKINT
ARTLITSLSGEKDRWGKGAQDISDQKRKLVGNVSLSTAFISYCGPFNAEY
RNKLAQQRFVVDMKKRGVPVTPGLELTSFLIDDATIGEWNLQGLPKDDLS
IQNGIMVTNSARYPLFIDPQGQGQNWIRNKLSAITTLSHPKFKDMFLKYC
MESGLTLIVENIENEVDPMMDPVLELSKEFKLFMTCRLANPSFSPELSAK
TTIIDFTVTQSGLEQQLLGKVISKEQKALEDSLNQLLADVNQNQKDLQRL
DKNLLERLINSQGNLLDDTELMDVLNNTKTQAKEVAAKLIDAEIKTKEIN
EKREQYRPVAIRGSAIYFTMIEVSLVNWMYNSSLEQFLKLFIESIDLSEK
AQLPSNRVKNIISFLTFHVYRYVNRGLFEKDKITFILMMAFKILTTAGTI
SSGDVSLFLKSQKQISYLEDNQWLNILALSKPFFKELPDLISRSENQWRN
WIDKNDPENFPIPDFAESINQEKEIGSFISLCLVRSLRNDRTLIATQNFI
SNVLGKEFTDPISYPIEGIWQESSNMDPVLFLLSAGADPTSSIDELAKKK
KKFPCEKVSMGEGQERVARQVIMKGFVEGGWVILQNCHLGLKFMEEIETL
VSPINQIHEDFRLWITCEQHPKFPLGLLQKTLKVTNEPPKGLKAGLYKTF
TTIITQEFIDKVDHSNWRSLIFTICFLHSIVIERKKFGPLGWCVPYEYNY
SDLEASLLYIEKYLTNLMSTPQPNSHNLPISMNVVRYMICEVQYGGRITD
DLDRELFITYGETYLKDGIFGNDYFFPQNPSAELIKYQEYIAKVPTVDNP
EVFGLHSNADLTFRLKESKEMINTVMETRPREEIVQDKAKDMLKNLPPDY
NDVEVRELVSKLGGPNPKTSTERGMTVPLNIFLYQEVTRMQRVIGLVRKT
LQDTILAIDGQIIMTPEILEAINAIYDAKVPNSWLYDPSGAEISWLLPNL
GSWSTSLSDRNKQLNDWLRSGQRPILFWLTGFFNPQGFLTGMKQEVTRNH
KKEAWSLDDVVYSTTVKEREKEPAEGVYIKGLYLEGCKWSKNGLDDSDPK
KIFADLPILHVSAINKSNTYLCPVYKYPKRTDKYLIFRVGLPCEGSNNPS
HWKLRGVALLCSTE
3D structure
PDB8bwy ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
ChainC
Resolution38.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C G2869 G2870 S2871 G2872 Q2874 S2875 G2630 G2631 S2632 G2633 Q2635 S2636
BS02 ADP C L2461 G2496 T2497 A2498 K2499 L2222 G2257 T2258 A2259 K2260
BS03 ADP C A1874 G1875 G1877 K1878 A1635 G1636 G1638 K1639
BS04 ATP C L2130 I2131 G2162 K2163 S2164 L1891 I1892 G1923 K1924 S1925
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008569 minus-end-directed microtubule motor activity
GO:0016887 ATP hydrolysis activity
GO:0045505 dynein intermediate chain binding
GO:0051959 dynein light intermediate chain binding
Biological Process
GO:0007018 microtubule-based movement
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0005929 cilium
GO:0030286 dynein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bwy, PDBe:8bwy, PDBj:8bwy
PDBsum8bwy
PubMed37051721
UniProtQ22A67

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