Structure of PDB 8bsu Chain C

Receptor sequence
>8bsuC (length=252) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIR
LVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITAVREKAIDFSKP
FMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTF
EKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLT
QIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSG
CP
3D structure
PDB8bsu Positive allosteric modulation of homomeric kainate receptors GluK1-3
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2J9 C I93 P106 S214 K215 G216 I87 P100 S208 K209 G210
BS02 2J9 C K105 P106 F107 M108 T109 L236 Q239 K99 P100 F101 M102 T103 L230 Q233
BS03 ZN C E44 H47 E38 H41
BS04 KAI C E15 Y63 P90 T92 R97 G142 A143 T144 N174 E191 E9 Y57 P84 T86 R91 G136 A137 T138 N168 E185
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8bsu, PDBe:8bsu, PDBj:8bsu
PDBsum8bsu
PubMed38145505
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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