Structure of PDB 8bav Chain C

Receptor sequence
>8bavC (length=264) Species: 9606 (Homo sapiens) [Search protein sequence]
GRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANL
HKVKQQFMTTSKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQ
IWRKYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFD
RNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVS
KTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQ
KSELALCLGLKINP
3D structure
PDB8bav Calmodulin type regulator (Homo sapiens) with peptide ligand
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C D118 D120 S122 F124 E129 D106 D108 S110 F112 E117
BS02 CA C D162 N164 D166 R168 D150 N152 D154 R156
BS03 CA C D210 S212 T214 A216 E218 E221 D198 S200 T202 A204 E206 E209
BS04 CA C D254 N256 D258 K260 Q262 E265 D242 N244 D246 K248 Q250 E253
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration
GO:1900271 regulation of long-term synaptic potentiation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0030425 dendrite
GO:0030658 transport vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0043195 terminal bouton
GO:0045202 synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bav, PDBe:8bav, PDBj:8bav
PDBsum8bav
PubMed38593081
UniProtO76038|SEGN_HUMAN Secretagogin (Gene Name=SCGN)

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