Structure of PDB 8b5b Chain C

Receptor sequence
>8b5bC (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDA
VKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY
NKPGDDIVLMAEALEKLFLQKINELPT
3D structure
PDB8b5b Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family.
ChainC
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C W81 V87 L92 N93 D96 I138 Y139 N140 D145 I146 M149 W42 V48 L53 N54 D57 I99 Y100 N101 D106 I107 M110
External links
PDB RCSB:8b5b, PDBe:8b5b, PDBj:8b5b
PDBsum8b5b
PubMed36585954
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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