Structure of PDB 8b4l Chain C

Receptor sequence
>8b4lC (length=311) Species: 1901 (Streptomyces clavuligerus) [Search protein sequence]
ADMTISVPQLDCPLSRPVHPEGERADAYAVEWLRGVGLMADEADAAPVLA
VGLGRLAACYVDENASWDTLAFMTILLAWYAEYDDRAIDSTDGLTDAEVA
ELHRALGEILRDRPAPDPSDPVQRGLADVWRTLNGLASDWDRAAFVDTTL
RYFEANRYERVNIRRGIPPTPSAHIGMRRHGGHVYGMYILGAAVNGYRPE
RRVLDHAAVRELETLAANYTSWANDLHSFAREHRMGQVNNLVWSVHHHEG
LTFQQAADRVADLCDKELAAYLELRQTLPELGIPLTGATGRHVRFLEDMM
WSMVDWSARSA
3D structure
PDB8b4l crystal structure of s hydropyrene synthase in its closed conformation
ChainC
Resolution3.394 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.201: hydropyrene synthase.
4.2.3.202: hydropyrenol synthase.
4.2.3.203: isoelisabethatriene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D82 D87 D84 D89
BS02 MG C N225 S229 E233 N224 S228 E232
BS03 MG C D82 D87 D84 D89
BS04 AHD C D82 R179 N225 S229 D84 R178 N224 S228
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8b4l, PDBe:8b4l, PDBj:8b4l
PDBsum8b4l
PubMed
UniProtD5SK09|HPS_STRCL Hydropyrene synthase (Gene Name=SCLAV_p0765)

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