Structure of PDB 8ajj Chain C

Receptor sequence
>8ajjC (length=444) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
TYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSK
TLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFK
SNTEVNLLDQHDDIVDSITAPHIIINTGATSVIPNIKGLDQAKHVFDSTG
LLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQD
VVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNVDNFEADAVLLAI
GRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTY
ISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQ
HYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEE
LINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNFHHHHHH
3D structure
PDB8ajj MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
1.16.1.1: mercury(II) reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD C G10 G12 I32 E33 Q34 M38 G41 T42 G47 C48 K52 A99 N128 T129 G130 I171 R254 G292 D293 Q299 F300 T301 Y302 S304 G8 G10 I30 E31 Q32 M36 G39 T40 G45 C46 K50 A97 N126 T127 G128 I169 R252 G290 D291 Q297 F298 T299 Y300 S302
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Biological Process
GO:0045454 cell redox homeostasis
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ajj, PDBe:8ajj, PDBj:8ajj
PDBsum8ajj
PubMed36779383
UniProtQ2G0I4

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