Structure of PDB 8aai Chain C

Receptor sequence
>8aaiC (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
DPREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQ
INGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVG
FIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILST
SGTVVTITIMPA
3D structure
PDB8aai Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
ChainC
Resolution2.76 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 LKV C S259 T260 S149 T150
BS02 LKV C H208 V209 G210 F211 I212 F213 D251 H98 V99 G100 F101 I102 F103 D141
External links
PDB RCSB:8aai, PDBe:8aai, PDBj:8aai
PDBsum8aai
PubMed36939673
UniProtO00560|SDCB1_HUMAN Syntenin-1 (Gene Name=SDCBP)

[Back to BioLiP]