Structure of PDB 7zdb Chain C

Receptor sequence
>7zdbC (length=554) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAG
VAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTF
SKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMV
VTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYR
QQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAI
MLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGA
FQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPE
QSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQQLTRAWDPQQGEILLN
DSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEIL
RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDE
PTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQI
IEQG
3D structure
PDB7zdb IF(heme/bound) conformation of CydDC in ADP+Pi(CydC)/ATP(CydD) bound state (Dataset-2)
ChainC
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEB C R81 H85 H132 L135 R81 H85 H132 L135
BS02 MG C S380 Q421 S380 Q421
BS03 ADP C Y348 G376 G378 K379 S380 Y348 G376 G378 K379 S380
BS04 PO3 C K379 E500 H531 K379 E500 H531
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015439 ABC-type heme transporter activity
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0033228 cysteine export across plasma membrane
GO:0034775 glutathione transmembrane transport
GO:0035351 heme transmembrane transport
GO:0045454 cell redox homeostasis
GO:0055085 transmembrane transport
GO:1903605 cytochrome biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding

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Cellular Component
External links
PDB RCSB:7zdb, PDBe:7zdb, PDBj:7zdb
PDBsum7zdb
PubMed37095238
UniProtP23886|CYDC_ECOLI Glutathione/L-cysteine transport system ATP-binding/permease protein CydC (Gene Name=cydC)

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