Structure of PDB 7z6r Chain C

Receptor sequence
>7z6rC (length=206) Species: 334543 (Psychrobacter arcticus) [Search protein sequence]
FLGLTLALSKGRILEETMPLLRAAGVELLEDPEASAKLIFPTSNPNVRVL
ILRASDVPTYVEHGAADFGVAGKDVLLEHGANHVYELLDLKIAQCKLMTA
GVKDAPLPRRLRIATKYVNVARAYFASQGQQVDVIKLYGSMELAPLVGLG
DLIVDVVDTGNTLRANGLEARDHICDVSSRLIVNQVSYKRKFALLEPILD
SFKNSI
3D structure
PDB7z6r Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation.
ChainC
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C R32 D94 A113 C115 V177 D179 R12 D74 A93 C95 V156 D158
BS02 PRP C R32 V177 V178 D179 T180 G181 T183 R12 V156 V157 D158 T159 G160 T162
Gene Ontology
Molecular Function
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z6r, PDBe:7z6r, PDBj:7z6r
PDBsum7z6r
PubMed36494361
UniProtQ4FQF7|HIS1_PSYA2 ATP phosphoribosyltransferase (Gene Name=hisG)

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