Structure of PDB 7z50 Chain C

Receptor sequence
>7z50C (length=181) Species: 10090 (Mus musculus) [Search protein sequence]
IEADHVGFYGTTVYQSPGDIGQYTHEFDGDELFYVDLDKKKTVWRLPEFG
QLILFEPQGGLQNIAAEKHNLGCLTKRSNFTPATNEAPQATVFPKSPVLL
GQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLS
YLTFIPSDDDIYDCKVEHWGLEEPVLKHWEP
3D structure
PDB7z50 Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes.
ChainC
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C Y10 I54 L55 F56 Q63 N64 A67 H70 N71 C74 R78 Y9 I53 L54 F55 Q62 N63 A66 H69 N70 C73 R77
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7z50, PDBe:7z50, PDBj:7z50
PDBsum7z50
PubMed35967292
UniProtP04228|HA2D_MOUSE H-2 class II histocompatibility antigen, A-D alpha chain (Gene Name=H2-Aa)

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