Structure of PDB 7ysu Chain C

Receptor sequence
>7ysuC (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
TGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRG
EHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLE
RSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSK
VGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGF
SHHSAWLVVLP
3D structure
PDB7ysu Structural basis for FGF hormone signalling.
ChainC
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDS C R157 R160 R8 R11
BS02 SGN C R175 R177 Q212 R26 R28 Q63
BS03 IDS C R175 R209 Q212 R26 R60 Q63
External links
PDB RCSB:7ysu, PDBe:7ysu, PDBj:7ysu
PDBsum7ysu
PubMed37286607
UniProtP22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 (Gene Name=FGFR3)

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