Structure of PDB 7yev Chain C

Receptor sequence
>7yevC (length=1088) Species: 538123 (Mammalian orthoreovirus 3) [Search protein sequence]
GYQCHVCSAVLFSPLDLDAHVASHLTSSEIQRHITEFISSWQNHPIVQVS
ADVENRKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFF
TSSYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFK
QLLNTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFT
EGANLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDR
AQMMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTEC
AQGYVTVTSPYAPSVNRLMPYRISNAERQISQIIRVMNIGNNATVIQPVL
QDISVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNS
DFSSFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALAL
PLTTDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPR
CFMNIQLISPIDAPILRQWAEIIHRYWPNPSQIRYGTPNVFGSANLFTPP
EVLLLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWT
QSLVSSMRGTLGKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYV
RLDRDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVAL
LSGKYPPDLVTNVWYADAIYPMYADTEVFSNLQRDVITCEAVQTLVTLVA
QISETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEP
LLSGDPRMTQLAIQYQQYNGRTFNVIPEMPGSVIADCVQLTAEVFNHEYN
LFGIARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFG
MNGAAPMIRDETGMMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELR
IRIEMGAYPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISS
DHDISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILT
NPDAPPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGV
3D structure
PDB7yev In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
ChainC
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C C183 V185 H203 C4 V6 H24
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0019028 viral capsid
GO:0039625 viral inner capsid

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7yev, PDBe:7yev, PDBj:7yev
PDBsum7yev
PubMed36469786
UniProtC9E874

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