Structure of PDB 7yed Chain C

Receptor sequence
>7yedC (length=1086) Species: 538123 (Mammalian orthoreovirus 3) [Search protein sequence]
GYQCHVCSAVLFSPLDLDAHVASHGLHGNMTLTSSEIQRHITEFISSWQN
HPIVQAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFTSS
YAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQLL
NTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFTEGA
NLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRAQM
MNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECAQG
YVTVTSPYAPSVNRLMPYRISNAERQISQIIRVMNIGNNATVIQPVLQDI
SVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNSDFS
SFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPLT
TDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCFM
NIQLISPIDAPILRQWAEIIHRYWPNPSQIRYGTPNVFGSANLFTPPEVL
LLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQSL
VSSMRGTLGKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRLD
RDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLSG
KYPPDLVTNVWYADAIYPMYADTEVFSNLQRDVITCEAVQTLVTLVAQIS
ETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLLS
GDPRMTQLAIQYQQYNGRTFNVIPEMPGSVIADCVQLTAEVFNHEYNLFG
IARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFGMNG
AAPMIRDETGMMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIRI
EMGAYPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISSDHD
ISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNPD
APPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGVP
3D structure
PDB7yed In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C C183 H199 H203 C4 H20 H24
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0019028 viral capsid
GO:0039625 viral inner capsid

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7yed, PDBe:7yed, PDBj:7yed
PDBsum7yed
PubMed36469786
UniProtC9E874

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