Structure of PDB 7y5c Chain C

Receptor sequence
>7y5cC (length=505) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
IEGAIEDYVSSFREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGV
ALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSVPVGDAFLGRVVNPLG
QPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQTGIKAIDAMTPIGRG
QRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPKQQVRCVYVAIGQKGTT
IASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGSAIGQHWMYNGK
HVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKL
SDELGGGSMTGLPIIETKANDISAFIPTNVISITDGQCFLESDLFNQGVR
PAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDA
ASKAQLDRGARLVELLKQPQYSPLAVEEQVVAIFLGTQGHLDSVPVEDVQ
RFESELLEHVKASHSDIFDGIRETKKLSEEAEEKLVSVINEFKKGFQASD
GSSVV
3D structure
PDB7y5c Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
ChainC
Resolution4.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C K175 T176 G177 T179 F360 R365 P434 Q435 K160 T161 G162 T164 F345 R350 P419 Q420
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7y5c, PDBe:7y5c, PDBj:7y5c
PDBsum7y5c
PubMed36445139
UniProtA0R202|ATPA_MYCS2 ATP synthase subunit alpha (Gene Name=atpA)

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