Structure of PDB 7xy9 Chain C

Receptor sequence
>7xy9C (length=344) Species: 29323 (Thermoanaerobacter brockii) [Search protein sequence]
HHKGFAMLSIGKVGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAI
GERHNMILGHEAVGEVVEVGSEVKDFKPGDRVVVPANTPDWRTSEVQRGY
HQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIP
DMMTTGFHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVGS
RPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAAIIAGGNADIM
ATAVKIVKPGGTIANVNYFPRLEWGCGMAHKTIKGGLCPGGRLRMERLID
LVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVIL
3D structure
PDB7xy9 Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions
ChainC
Resolution2.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.80: isopropanol dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C G297 G298 L300 R301 G290 G291 L293 R294
BS02 MG C H100 H102 H157 C295 H101 H103 H158 C288
BS03 ZN C C37 H59 E60 D150 C38 H60 E61 D151
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050009 isopropanol dehydrogenase (NADP+) activity

View graph for
Molecular Function
External links
PDB RCSB:7xy9, PDBe:7xy9, PDBj:7xy9
PDBsum7xy9
PubMed37055470
UniProtP14941|ADH_THEBR NADP-dependent isopropanol dehydrogenase (Gene Name=adh)

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