Structure of PDB 7xhx Chain C

Receptor sequence
>7xhxC (length=216) Species: 562 (Escherichia coli) [Search protein sequence]
LPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTA
KDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTN
ELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKI
LFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPGHSEVGDA
SLLKLTLEQAVKGLNE
3D structure
PDB7xhx Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-beta-lactamases.
ChainC
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C H77 H79 H139 H74 H76 H136
BS02 ZN C D81 C158 H197 D78 C155 H194
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7xhx, PDBe:7xhx, PDBj:7xhx
PDBsum7xhx
PubMed36174533
UniProtK4PWX3

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